Best Sleep Supplements

10 Best Sleep Supplements Besides Melatonin

Dr. Jolene BrightenPublished: Last Reviewed: Herbs & Supplements, Sleep, Wellbeing Leave a Comment

Poor sleep affects all aspects of life and health. You’ve likely noticed how even one night of poor sleep affects your mood, energy, and hunger the following day. When poor sleep becomes chronic, the days can feel impossible to get through. 

Sleep is critical for learning, memory, metabolic health, healthy aging, hormone balance, and overall health. When you’re snoozing, it may not look like you’re doing much, but that’s when your body detoxifies, rebuilds, and repairs. It’s also a crucial time for hormones, like melatonin and growth hormone, to do their job. 

When sleep is optimal, it’s easy to fall asleep, fall back asleep if you wake up in the night, and wake up feeling rested, refreshed, and able to function optimally during the day. And getting seven to nine hours per night is the sweet spot for sleep timing. 

The bad news is that over 35% of American adults don’t get at least seven hours of sleep per night. Access to technology, overwork, and stress are just a few reasons that make it hard to prioritize sleep. 

When we don’t get enough sleep, we are at increased risk for:

It’s no wonder that so many of us are looking for ways to improve sleep. If you want to know how to get better sleep, keep reading to learn more about the best sleep supplements. 

progesterone and sleep

How to Sleep Better? Balance Your Hormones

If you’re looking for how to sleep better or get better sleep, your hormones may be worth investigating. Both the hormones that are responsible for menstrual cycles and healthy pregnancies, along with an appropriate stress response can influence your quality of sleep. 

Progesterone for Better Sleep

Progesterone rises after ovulation and stays up through the end of the luteal phase. But when progesterone levels fail to reach their ideal levels, sleep problems can show up. In fact, difficulty falling and staying asleep can be a sign of low progesterone. That’s because progesterone metabolites support the brain’s use of GABA, a neurotransmitter that helps us get our best sleep. Keep reading because I’m going to share supplements that can support your natural GABA.

While we want to address the cause of low progesterone in our cyclical years, there’s no denying the progesterone drop that happens in perimenopause and menopause. It may be necessary to supplement with progesterone during this phase of life (of course, talk with your provider). But the supplements listed below may also help you get better sleep by supporting your body’s GABA levels.

Cortisol Sleep Problems

The way it is supposed to work is that cortisol declines in the night while melatonin rises. But in some cases, stress hormones from the adrenal glands stay up and melatonin stays down in the evening hours. This is why dark rooms, avoiding screens, and chilling out before bed is so important. 

Taking supportive supplements to aid your body in the natural cortisol decline can also help promote restful and restorative sleep. We’ll talk more about those soon. 

Sleep Supplements

Let’s look at natural supplements to improve sleep. Consider these options while putting other sleep support in place, like establishing a bedtime routine, getting to bed earlier, and limiting stress and screens before bed. 

Sleep supplements provide gentle alternatives to stronger sleep interventions , which may cause side effects and dependency. 

Be sure to work with your provider to determine which options are the best fit for you. 

The top 10 sleep supplements (that do not contain melatonin) include: 

  • Ashwagandha
  • Magnesium
  • Taurine
  • Lemon balm
  • Valerian
  • L-theanine
  • Passionflower
  • Phosphatidylserine
  • Vitamin B6
  • Vitamin B12

Now, let’s discuss each natural sleep aid on the list. 

Ashwagandha for Sleep

Ashwagandha (Withania somnifera) is an adaptogenic herb often used for adrenal and thyroid support. It has a long history of use in Ayurvedic medicine and comes with many benefits, including the potential to reduce stress, feelings of anxiousness, and symptoms related to depression. 

Ashwagandha is in the nightshade family, like tomatoes and peppers, but the root of the plant is used for its medicinal properties. Ashwagandha can be taken in a capsule or you can add the powdered root to smoothies or teas. The name “ashwagandha” translates to “smell of horse,” so it may be easier to swallow an ashwagandha capsule than to sip on a tea. 

As an adaptogen, one of the main ashwagandha benefits is its ability to help us adapt and build resilience to stress. Stress can be a root cause of poor sleep. 

But does ashwagandha help you sleep? The answer seems to be yes! 

Many studies have looked at using ashwagandha for sleep, supporting that supplemental ashwagandha helps improve sleep quality and reduces the time it takes to fall asleep. One study showed that sleep quality improved by 72% after only six weeks. 

A meta-analysis of five trials suggests that in addition to sleep improvement in general and specifically for those with insomnia, ashwagandha also improved mental alertness in the morning and reduced anxiety. 

So, if you are tired and wired or can’t get going in the morning, ashwagandha might be a good fit. Note that it isn’t for use in pregnancy or with certain autoimmune conditions like lupus. 

The ashwagandha dosage for sleep is 100-200mg of standardized extract containing 5% withanolides.

You’ll find Ashwagandha in our Adrenal Calm formula, which is designed to take at night to promote restful and restorative sleep. 

Magnesium for Sleep

Magnesium is an essential mineral that has a calming effect on the body. Magnesium benefits include muscle relaxation and relaxing the nervous system. 

Most of us aren’t getting enough magnesium in our diets to meet our daily needs. In fact, over 52% of Americans aren’t eating enough magnesium. Those who eat enough rich sources of magnesium, like leafy greens, legumes, and avocados, may be getting less than they think due to depleted soil from modern farming practices. 

Nearly 50% of older adults have insomnia. Could part of the reason be a lack of magnesium? As we get older, we are more likely to have a lower intake of essential nutrients and a more challenging time absorbing them. 

We know that low magnesium status could contribute to poor sleep, and studies show that replenishing magnesium using magnesium supplements may improve sleep. 

When choosing a magnesium supplement for sleep, I prefer magnesium glycinate for better absorption and bioavailability. Start with 100-200mg and increase to reach the desired effect. 

If you find yourself making extra bathroom trips, check the label of your supplement. Loose stools is a known side effect of magnesium citrate, which is why I prefer the glycinate form. 

Taurine for Sleep

Taurine is an amino acid found in protein-rich foods. One of my favorite taurine benefits is that it in some cases acts like a calming neurotransmitter, although its receptor has yet to be identified. 

Taurine is similar in structure to glycine and GABA, with GABA being the body’s primary inhibitory or calming neurotransmitter. Taurine may interact with GABA receptors to inhibit the excitement of neurons, producing a calming effect. Taurine is also involved with melatonin metabolism. These mechanisms may help explain why taurine is an effective sleep supplement for some people. 

Supplemental doses of taurine start around 300mg and go as high as 3 grams. 

10 sleep supplements

Lemon Balm for Sleep

Lemon balm (Melissa officinalis) is an aromatic herb in the mint family that is considered a nervine because it calms and rejuvenates the nervous system. You’ll see lemon balm used in herbal teas, herbal formulas, and supplements. 

Lemon balm benefits include supporting digestion, easing anxiety, and promoting sleep. As a sleep aid, lemon balm (and its active constituent rosmarinic acid) acts on the GABA system in the body to improve sleep quality. 

Lemon balm is a gentle option. Try lemon balm for sleep as an herbal tea enjoyed before bed or as a supplement. Look for lemon balm with a standardized 3% extract of rosmarinic acid. The starting dose is 100mg. 

Valerian Root for Sleep

Valerian root (Valeriana officinalis) is another nervine herb, although it is stronger than lemon balm and is more of a sedative. It’s the root of the plant used to make medicine. 

Valerian is most well-known for its sleep benefits and is commonly used throughout the globe. It interacts with the GABA receptor, like many of the supplements on this list, to help calm the nervous system response. Valerian has been shown to reduce time it takes to fall asleep and improve subjective measures of sleep quality. 

When choosing valerian root for sleep issues, choosing a standardized product is important. Some of the active constituents in valerian are unstable and quality may vary among herbal products. A starting dose is 100mg standardized to contain 0.8% valerenic acid. 

L-Theanine for Sleep

L-theanine is an amino acid found in high concentrations in green tea. It’s known to have a calming effect and offsets the stimulating effects of caffeine in green tea, which is why some people prefer it over coffee. 

L-theanine benefits include easing stress, calming anxiousness, and improving mental focus. It can also be used as a supplement to support sleep. L-theanine on its own or in combination with other sleep support such as GABA may improve sleep quality. 

One study showed that an L-theanine and GABA mixture reduced the time it took to fall asleep, increased sleep length, and improved both REM and non-REM sleep. Another study showed that l-theanine supplementation improved sleep and other stress-related symptoms and cognitive function. Effective dosages start around 100 to 200mg. 

Passionflower for Sleep

Passionflower (Passiflora incarnata) is another nervine herb that may support sleep by acting on  GABA receptors and soothing the nervous system. Passionflower has been shown to reduce the time it takes to fall asleep and increase sleep duration. 

In one study, passionflower tea was given before bed, showing subjective sleep benefits according to participants’  sleep journals. 

Additional passionflower benefits include calming feelings of anxiousness, which can make sleep more challenging. Compared to an anxiety medication, passionflower helped manage symptoms without impairing job performance. 

Many women turn to passionflower for sleep support during pregnancy, as it is generally considered safe to use during the fertility journey, pregnancy, and postpartum. In this case, tea or a tincture is most often used. 

The passionflower dosage for sleep in supplemental form is 100mg standardized to contain 3.5% flavonoids.

l-theanine benefits for sleep

Phosphatidylserine for Sleep

So far, we’ve discussed herbs, amino acids, and the mineral magnesium. Phosphatidylserine is a phospholipid, one of the molecules found in cell membranes, important for cellular health and communication. 

It is possible that phosphatidylserine benefits sleep also, particularly for those with sleep difficulties related to stress and elevated cortisol levels in the evening. Ideally, we want cortisol to be low at night to promote sleep, and phosphatidylserine supplementation may help to dampen the cortisol response.

If you have PMS and have a hard time sleeping prior to your period, phosphatidylserine for sleep support might be worth a try. Women taking phosphatidylserine for three cycles showed a reduction in PMS symptoms compared to placebo. 

Vitamin B6 for Sleep

Now, let’s explore a couple of sleep vitamins. Vitamin B6, and its active form pyridoxal 5’-phosphate (PLP), are involved in protein metabolism, including the reactions that synthesize neurotransmitters. PLP is needed to produce serotonin, which converts to melatonin, supporting sleep. 

Vitamin B6 may also affect hormone balance, mood, brain health, and immunity. 

In one study where participants took vitamin B6 for sleep, they reported enhanced dreaming and recall of dreams. 

The recommended daily allowance (RDA) for adults is 1.3mg of vitamin B6 daily, although much higher dosages are used in supplemental form. A vitamin B6 dosage for sleep starts around 5mg and goes up to 240mg.. Because it’s water soluble, excess will be excreted via the urine, but in some people, toxicity can occur. To avoid this, do not supplement with more than 100 mg of vitamin B6 daily and talk to your provider.

Vitamin B12 for Sleep 

Another vital vitamin for sleep is vitamin B12. Vitamin B12 is essential for fertility, pregnancy, energy, brain health, and more. And deficiency is common in vegetarians and the elderly. 

Vitamin B12 and sleep also have a relationship as the vitamin impacts neurotransmitters and the circadian rhythm. One study found that students with better B12 status scored higher on a sleep quality scale and were less likely to use sleep medication. 

Another recent study found no relationship between vitamin B12 and sleep over two weeks. However, this study used the cyanocobalmin form of B12 instead of the active (and preferred) methylcobalamin form. 

The RDA for vitamin B12 is 2.4 micrograms for adults, and like the other B vitamins, you’ll see higher dosages in supplements. For example, Adrenal Calm contains 2000 mcg. 

sleep and adrenal imbalance

All-In-One Supplement for Better Sleep

If you follow me on social media, then you know  Adrenal Calm is my BFF when I travel and well, every night. I love this supplement for its calming and relaxing benefits. It’s designed to support the HPA-axis and adrenal glands as well as promote healthy sleep. It contains many of the sleep herbs and nutrients I’ve covered here. 

Adrenal Calm contains:

  • Vitamin C
  • B vitamins – including vitamin B6 and B12
  • Magnesium
  • Taurine
  • L-theanine
  • Lemon balm
  • Passionflower
  • Valerian 
  • Ashwagandha
  • Phosphatidylserine 

This formula is my go-to when I need a chill pill. It’s especially helpful during high stress, when I want to secure a good night’s sleep, and to help me wake with enough energy to keep up with my kids. The synergistic blend of adaptogenic and nervine herbs, along with vitamins, amino acids, and phosphatidylserine is deeply nourishing, relaxing, and calming. 

If you’ve been wondering how to sleep better and have been doing all the things right when it comes to the bedtime routine, give Adrenal Calm a try. It’s formulated to take 3 caps about an hour before bed.

Key Takeaways

  • Sleep is critical for health, but many people don’t get enough sleep or suffer from poor sleep quality. 
  • Luckily, we have many supplements to help with sleep, naturally and effectively. 
  • Supplements can be used individually or in a combination formula like Adrenal Calm
  • Be sure to work with your doctor when choosing sleep support supplements, especially if you take medication, have a medical condition, are pregnant, or nursing. 

Here’s to a good night’s sleep, tonight and every night!

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About The Author

Dr. Jolene Brighten

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Dr. Jolene Brighten, NMD, is a women’s hormone expert and prominent leader in women’s medicine. As a licensed naturopathic physician who is board certified in naturopathic endocrinology, she takes an integrative approach in her clinical practice. A fierce patient advocate and completely dedicated to uncovering the root cause of hormonal imbalances, Dr. Brighten empowers women worldwide to take control of their health and their hormones. She is the best selling author of Beyond the Pill and Healing Your Body Naturally After Childbirth. Dr. Brighten is an international speaker, clinical educator, medical advisor within the tech community, and considered a leading authority on women’s health. She is a member of the MindBodyGreen Collective and a faculty member for the American Academy of Anti Aging Medicine. Her work has been featured in the New York Post, Forbes, Cosmopolitan, Huffington Post, Bustle, The Guardian, Sports Illustrated, Elle, and ABC News. Read more about me here.