Can a GLP-1 medication change the way progesterone works in endometriosis? That is the central question Dr. Brighten explores in this episode, and it is not a throwaway idea. It sits at the intersection of inflammation, hormone receptor signaling, and the reality that many women are told to manage endometriosis with options that reduce symptoms without stopping the disease process. …
ADHD, Motherhood, and Invisible Overload
Before we get started, I want to share something I’ve been working on with you. My new book, ADHD and Women, was born out of years of seeing women struggle with symptoms that are often overlooked, misdiagnosed, or dismissed entirely. So much of the conversation around ADHD has been centered on men, and it leaves women without clear answers. In …
Perimenopause Sleep Hormones: Cynthia Thurlow on Why Rest Changes First
What if the first sign that perimenopause is shifting hormones is not a hot flash, but broken sleep? For many women, the earliest clues are more subtle: waking at 2 a.m., feeling wired but tired, noticing more palpitations, or realizing that brain fog and irritability are showing up alongside restless nights. In this episode, Dr. Jolene Brighten sits down with …
Fertility Protocol for Conception: Labs, Nutrition & Proven Strategies
What if targeted, evidence-informed changes to daily habits could improve your chances of conceive without turning your life upside down? In this episode, I walk you through a practical fertility protocol that centers metabolic health, ovulatory function, and simple habit shifts that actually stick. I focus on what the data shows is most actionable—which labs to run and how to …
Dry Eye Relief: What’s Causing Your Dry, Gritty Eyes (and the Simple Routine That Helps) | Dr. Carly Rose
Most dry eye treatment focuses on drops. This episode is about what drops don’t fix — and the daily habits that actually change things. In this episode of The Dr. Brighten Show, Dr. Jolene Brighten talks with Dr. Carly Rose (Dr. Rose) about what dry eye really is, why it keeps showing up, and what actually helps. Dry eye is …
What Is ADHD Masking? The Perimenopause ADHD Connection
If you’ve ever wondered why you used to be able to hold it all together and now suddenly feel like your brain is working against you, this episode will hit home. In this conversation, Dr. Brighten unpacks the reality of ADHD masking, why so many women go decades without a diagnosis, and how perimenopause ADHD symptoms can make long-standing coping …
Skin Aging Treatment and Skin Microbiome: What “Leaky Skin” Could Be Telling You About Inflammation, Hormones, and Healthy Aging | Kiran Krishan
What if the condition of your skin was saying far more about your health than whether you need a new moisturizer? In this conversation, Dr. Jolene Brighten sits down with microbiologist Kiran Krishan to unpack a provocative idea: that skin barrier dysfunction may be linked not only to dryness, wrinkles, and hyperpigmentation, but also to systemic inflammation, hormone shifts, gut …
Can Ozempic and GLP-1’s Help Treat Endometriosis
f you’ve been wondering whether Ozempic, semaglutide, tirzepatide, or other GLP-1 medications could help with endometriosis symptoms, chronic pelvic pain, adhesions, fatigue, or endo belly, you are not alone. More and more women with endometriosis are reporting that GLP-1 medications may be helping with symptoms that go far beyond weight loss, from lower inflammation and less pain to improved energy …
Birth Control for Endometriosis? Hormones, Progesterone Resistance, and What Doctors Aren’t Telling You
If you’ve ever been told to “just go on birth control” for endometriosis, this episode is going to change the way you understand endometriosis and hormones. Hormonal therapy is often the first-line treatment for endometriosis, but not all hormones work the same way and for many women, birth control helps symptoms without ever addressing the underlying disease. In this powerful …








