Peptides for Hair Loss & Skin Aging Reversal: OneSkin Review

[00:00:00] Carolina Reis Oliveira: ninety percent of how our skin and age is in our control the accumulation of aging cells these are just cells that stop functioning well and induce the cells around to age fat sir so they can also become zombie cell

[00:00:16] Dr. Brighten: excess sugars also connected to the increase in visceral adi for women which also increases inflammation

[00:00:23] Carolina Reis Oliveira: skin is a reflection of our internal health it's like a two way approach that i think we all needed to be aware

[00:00:30] Dr. Brighten: of after menopause because about a thirty percent reduction in your collagen we start to lose the integrity of our skin

[00:00:38] Narrator: doctor caroline na rivera is the ceo of and c founder of one skin leading groundbreaking work and longevity and healthy aging with a phd in immunology and her pioneering os zero one peptide the first proven to reverse skin biological age she's reshaping how we think about aging from the outside in we have done its studies for cosmetic treatments we tested the peptide we saw an improvement in the bare of the skin and we saw more prone reduction in fine and wrinkles in radian

[00:01:10] Dr. Brighten: there's lifestyle choices that can accelerate skin aging what are like the things that we should consider avoiding

[00:01:18] Carolina Reis Oliveira: based on my studies in my research in the field is that first rule obviously is avoid

[00:01:24] Dr. Brighten: welcome to the doctor bright show where we burn the b in women's health to the ground i'm your host doctor jo b and if you've ever been dismissed told your symptoms are normal or just in your head or been told just to deal with it this show is for you and if while listening to this you decide you like this kind of content i invite you to head over to doctor wright dot com where you'll find free guides twice weekly podcast releases any ton of resources to support you on your journey let's dive in you have been in the skin care industry for a very long time so the juicy question i have for you is what is something that you were doing maybe it was a care routine or using a product that you thought was so great for your skin but then it turned out to be the worst thing you were doing for your skin

[00:02:12] Carolina Reis Oliveira: yeah that's an interesting story one of the products that i was using sin and young age is like re acid because i the acne growing up and then eventually when i was i was in my twenties i i continue to use for its anti aging benefits and the think that i was always like red and peeling and i was like that's fine i'm like just this skin that's how it's supposed to be and then when we started testing peptides and molecules in the and we used like red retina acid as a positive control i saw like genes associated with inflammation and aging going up and i was like well i was using this you're like rejuvenate these skins and those jeans are going up so like what's going on here so from that time on i stop it for a while and i realized that i was over using right now because what it happens is that if you stop your skin can you know adjust and then you you shouldn't be red and like peeling all the time it's okay that adaptation phase but i was i think i was over using because i was always like with redness and you know a little bit of irritation and i thought that was fine and then later on i realized no i was like doing too much into my skin and when you have like prolonged redness and inflammation is definitely not good for your skin so the my main advice for people that are used right now it's make sure that your skin can adapt to it and that you can now combine with a product that counteract those side effects the inflammation the redness and hydration because that's another thing i was not using like a very good moisturizer so i was just peeling out the time and i thought that that was right and then later on i realized well no that's not how you do it and today i understand how important is to have like you know to preserve your skin barrier so make sure that your skin is not super exposed because your skin needs to be strong to to protect you know your internal body and if you're constantly peeling you're basically getting rid of that barrier and your skin gets more exposed and so that can lead it to a lot of issues that today i understand a lot better how we should take care of our skin in a way that yes we can still have the rejuvenation that we want but we don't need it to compromise our skin barrier we don't need it to be you know facing those redness and irritation all the time this is actually a sign from your skin hey you know stop and and let's this slow down for a little bit

[00:05:02] Dr. Brighten: mh okay so we're gonna get into re the skin and all the things that we can be doing but you said something in there i think made a lot of people just raised their eyebrows which is you said that using this vitamin a the re acid that you alluded to that was causing inflammation and you saw that in the lab can you say more about that

[00:05:25] Carolina Reis Oliveira: yeah so essentially what one of the things that we do we grow skin in the lab and we can replicate the skin aging and we test either like a a topical product or a specific molecule and we see how the skin behaves and we've red like acid or right it's very clear when we apply it on top of the skin we see the upper layer coming out we know that right now induces the sell renew so you're gonna basically share out the top layers and you're growing a newer fresh skin and as i said that's okay if it is for a short period of time

[00:06:05] Dr. Brighten: mh

[00:06:06] Carolina Reis Oliveira: and so what we saw and that feeling was happening genes associated with inflammation and aging were also going up meaning that you know instead of like turning those jeans off that's what we want you know to rejuvenate the skin they can be temporarily turned on and that can if it's sustained for long term that can be detrimental for your skin so that's you know one of the ways that we evaluate like ingredients and you know products to make sure that in the end we wanna deliver just benefits today's skin we don't wanna cause you know side effects and we definitely don't wanna compromise this skin health

[00:06:50] Dr. Brighten: mh with the re was it dose dependent in terms of activating pro aging genes or was it frequency dependent or was

[00:06:59] Carolina Reis Oliveira: it both definitely they hire those the the the they stronger the effect and in this in the lab we can only test like for short period of time so that's why i usually associated with the acute face that your skin is reacting to it and we cannot like keep the skin longer to see those jeans you know coming down but definitely the the stronger the red now or and obviously the prolong you know if you sustained the the exposure that will lead the to more inflammation so that's why we say that you should you know either cycle or make sure that you're skin adapts scene that kind of a low face building so your skin is not you know over reacting to it

[00:07:49] Dr. Brighten: what does it look like to cycle re and what other products should you be including in your routine to kind safeguard against these effects

[00:07:58] Carolina Reis Oliveira: yeah so cycle basically means like don't use it every day use like you know three depending on your skin like how much you can tolerate it but it starts like two three times a week and alternate when you feel that your skin is already strong and tolerate you could potentially use every day one of the tricks that i do if i wanna use it every day i apply my moisturizer first because then i feel that i have a layer of like protection and then i come with the red snow on top because if i do the red now first it's gonna maybe work faster but i also know that i will experience either the redness or or the peeling and i i don't want that so i either alternate or if i wanna use it more often i apply my you know os as one moisturizer first and the products that you should look to combine our products that will soothe your skin because the red milk can cause redness you wanna calm down you wanna reduce the inflammation you wanna hydrate your skin because also the retinal can cause dryness and the other thing is it's basically to increase like the they repair capacity of they skin and like the barrier building capacity so products with like ce who help you know repairing that barrier that the retinal may you know compromise for for the short term

[00:09:30] Dr. Brighten: mh i love that idea and i i also do this as well so it's really reassuring to hear that of putting a moisturizer first and then the re on tops i'm someone with sensitive skin so i always have to be careful of what i'm putting on there and it's funny because my dermatologist is like oh just put a little on your wrist and see how it reacts and i'm like it's like my body thinks my face is different from my neck is different from my chest and is definitely different from my wrist because i might put something my wrist and it's fine i put it on my chest not fine or my neck and it's like it's on this it's close from the face to the chest and yet and i think that you know some of us are just sensitive like that and so it's a good tip for people listening but i know that there's other ways that you can help with the anti aging process of the skin and again i love that you frame this of not about just how do we look but the barrier of the skin and i'm always trying to say that to my audience i've like your skin needs to be a healthy barrier to protect you it's your first line of defense from the outside world so with that in mind pregnant women women who are trying to conceive they can't be using this topical vitamin a there's other people too they're far too sensitive so what are some alternatives that people can consider

[00:10:48] Carolina Reis Oliveira: yeah so one of the things that we have been study studying for the past almost ten years are basically peptides and more specifically one peptide that would cover that can target the aging cells that build up in our skin so if we if we think of how aging happens in our skin in our whole body basically one of the key drivers is the accumulation of aging cells they are also called the zombie cells or cells these are just cells that stop functioning well so they should be secret collagen but they can't produce more collagen and they also start to to secret like inflammation and induce the cells around to age faster so they can also become zombie if you have like a zombie cell secret securing those bad signals and and to us like even if you have the retina nose or if you have your antioxidants if you're continue to accumulate those aging cells they basically creating that inflammation and aid you continue to spread inside your skin and when we were studying skin aging and testing the products that were out there like we didn't see any product that were was targeting these sen and zombie cells and we decided to look for a peptide that could specifically reduce the amount of these cells in the skin and what it happens is if you have like fewer of the cells you basically make room for the healthy the young ones to replicate and take produce collagen again and they restore your skin barrier and in a way that's very targeted it's very specific it doesn't disturb the healthy cell so it's not gonna cause any irritation or inflammation and in works basically from the inner layers from you know from the inside out in a way that goes like it it penetrate the skin and works from the inner layers to the top and you know goes like by all the layers of the skin that produce you know gives the firm ness and and the the collagen and and until to the top of like a strong barrier and a nice looking skin so i love this approach because it's one that it goes to the root cause and not only tries to mask the symptoms and it's it's again it's a specific and i think it's interest like peptides is very busy right now but not peptides are created equal and it's important to understand how that peptide works how that peptide is gonna activate the cells in a way that will produce a certain effect and that's why this peptide is effective in reducing this amount of aging cells which for us like everyone should be fighting those aging cells because they're gonna cause inflammation they're gonna you know cause tissue degeneration and it's not all in your skin in your whole body but i think this skin is one of the easiest just way that we can address them because you can apply a cream the peptide you know penetrate and words like on this site so peptides are safe for like people that are pregnant that are you know that are one of you know sensitive skin and and they can be really really effective and you know basically help your skin to to build up again that you know stronger healthier skin as as i said from they signed out

[00:14:28] Dr. Brighten: mh we had dermatologist doctor sarah she on the podcast and she was just praising peptides but not everyone may have caught that episode so can you explain what peptides are because they are all the rage but just because things were popular doesn't mean we get the definition around what they are

[00:14:48] Carolina Reis Oliveira: a hundred percent so peptides are essentially small pieces of protein so they are like little chains of amino acids and they they act as like a messenger they are gonna send a different messages to this cells in our bodies and that's the key because the more specific the message is the better cell will respond to that message and a lot of the peptides out there they are not specific and the general thought oh they it will improve you know cellular function to increase collagen but it most peptides out there they are not like the mechanism of action is not really understood this case the peptide that we found we know exactly how it works is gonna you know enter the cell is gonna send it this you know message to the cell shut off inflammation the inflammation is not good for the cell let's increase like the the dna repair pathways because we needed to protect ourselves against the the uv damage and all the that stress and and basically helps the cells activated that the natural repair system that the cell has and and so your skin is able to behave like younger skin again so i think again peptides can be very useful but you also need to make sure that they can get today's skin and and a lot of peptides can be you know a higher molecular molecular weight like a bigger size cannot penetrate the skin or they can be not stable enough so they enter and they degrade and so testing like the stability the ability to get into the deeper layers of the skin and how active the peptide is after certain period of time it's really key to make sure that you are still getting the benefits when a product like claims to have a peptide in it

[00:16:55] Dr. Brighten: mh you said though not all peptides are created equal there are so many peptides out there we're seeing people inject them but what you're talking about is a topical peptide if there's one peptide people should be looking for if they want to eradicate zombie cells and promote healthy skin over their lifetime is means there just one that someone could pick

[00:17:19] Carolina Reis Oliveira: so as far as we know and we've been studying this for the past nine years as i said the peptide data we developed os one that's publishing in scientific journals it's validated in clinical result in clinical studies is the only one proven to decrease the amount of these zombie cells in these schemes there are other ingredients out there there are plant extracts and and other products claiming to reduce the amount of sen and themselves i haven't seen the data that to really it so if if i at the moment that i see it i'll definitely share actually there is one product that's also based on ex and there is one study there's small study that the claims to reduce sen and sales and i saw the data so that one okay at least i saw the data but peptides as far as i know os as one is the only one that's like publish and validated to be able to be specific in reducing and sales as i said there are peptides that do other things but specifically targeting zombie cells as far as i know and i know that's is a new area of like research is growing so i'm sure that eventually more will come up but at this peptide that we develop it's been you know studied for the past like ninety years and that's one that we feel really really confident about the efficacy the safety and the the ability to do what it's supposed to do

[00:18:55] Dr. Brighten: have you seen any side effects with it that people should be aware of

[00:18:59] Carolina Reis Oliveira: we have not seen any side effects we have tested the peptide in different doses lower higher concentrations and the the peptide that it's it's really safe and not have you know promoted any toxicity and irritation so again that's one of the beauty of relying on peptides i would say like this peptide peptides more specific has not being shown inside effects

[00:19:29] Dr. Brighten: so i'm curious with applying this so so this os one peptide can penetrate the skin i'm curious though how long does it take to to start knocking out these zombie cells of course we're interested in that but i think my listeners are probably also like and when does my skin start looking better so i think that's a two part question of what have you seen in terms of your scientific research around this

[00:19:55] Carolina Reis Oliveira: yeah so in the lab we have seen result as as fast as like five days but also in the lab it's a very controlled condition but we we see that it reduces the load of sen cells and also we can measure what we call the skin biological agent and we can see mh turning the age of the skin these

[00:20:17] Dr. Brighten: in five

[00:20:18] Carolina Reis Oliveira: days five days but that

[00:20:20] Dr. Brighten: that's pretty incredible i know it's in the lab it's very very controlled so everyone listening you don't live in the lab so it's a little bit different but it's still pretty tremendous to see that kind of result in five days

[00:20:31] Carolina Reis Oliveira: yeah and that's the i think the beauty of sciences are like we we we call it like a proof of concept right like it it works in the lab in these conditions so now how we can translate the this into humans so in humans we have done is studies the classic studies for cosmetics are like three months so we tested the peptide we the we even did the like a split phase study with the full formula containing all the other ingredients that that are also very beneficial for the skin and half of the face containing also the peptide and we saw that in this half of the face we saw an improvement in the bearer of the skin that we didn't see the other side and we saw more pronounced reduction in fine and wrinkles and radian that was less you know pronounced in the side without the peptide and and we start seeing results around six weeks so usually in the beginning you were gonna see results first like in the texture of the skin in the softness and then with time you gonna basically see the results that are related to change basically the makeup of the skin right so you're gonna see the warm the plump ness the the the reduction in filings and wrinkles the the tone the the evening in pigmentation but more interesting than that we extend our studies just six months and twelve months yeah

[00:22:03] Dr. Brighten: i was gonna ask what happens if if it looks that good three months what happens like twelve months later

[00:22:09] Carolina Reis Oliveira: yeah so interesting very interesting we see that the results are compounding over time so we're seeing even if like we have this measurement that's called like medical grade evaluation so there's a pathologist that's looking at the patient and it's like grading their fine and wrinkles and we see that the reduction you know increases over time we see that the the firm increase your increases over time and and so it's really interesting first that we are like obviously following these participants for a long time yeah and second though we also collect like small pieces of their skin like small biopsies and we can look like internally at the the cellular level and we can see that we continue to reduce like the the sen essence you know cells the zombie cells and inflammation and improving collagen so it's one thing that we we really pride the sales of doing because for us it's it's not only focused on the near term benefits which we are you know expecting but how we're how are treating our skin to improve it in the long term and we we have this we call ourselves even like a long longevity company because we are we are working to help you to have your best skin not only today but you know in two years five years ten years from now we want yourself to be you know thankful for investing your skin in the right way with the right approach one that's like focusing and optimizing your houses so that's one thing that you know super very excited to share that i think is very unique of you know our studies in our company

[00:23:56] Dr. Brighten: mh and for everyone listening we will link to these studies in the show notes so if you wanna check them out yourself you said rad was one of the measurements like improved radian but how is that measured what it what does that mean because i think you know immediately when you said it i had an idea on my mind

[00:24:14] Carolina Reis Oliveira: and i'm sure people have ideas in their minds but how does the science measure improved radian yeah there are specific equipment that we use in clinical studies and these are studies that are done by third parties so we are not the ones that are actually measuring it which i think it's great because we have third party validation and so basically when your skin ages and becomes more dull you know you lose that radiant right and so when you recover like that moisture that barrier and your skin you know we we say this word that's like a little you know maybe overly use glowing it's basically

[00:24:55] Dr. Brighten: that's exactly the word i thought when you said radian i was like oh like glowing skin that you think about how in pregnancy everyone says like oh you're glowing so i was curious if that was that was part of the evaluation

[00:25:07] Carolina Reis Oliveira: yeah exactly so you'll feel that your skin is healthy like slump then and you know it's it's somewhat in some way like it's very joyful i i that's how i feel my skin like when i look at the mirror today i feel like wow my skin is so healthy i like you know touching it and i see them bouncing and and that's just like that the radiant that hours comes from within it within the way that your skin is healthy within and then it reflects in that way mh

[00:25:37] Dr. Brighten: what was the age of the participants in the study that showed these outcomes i'm i'm curious because as we know lots of estrogen and aging we start to lose the integrity of our skin our collagen declines we know that after menopause within that first five years it's about a thirty percent reduction in your collagen so i'm just curious like what age demographic were you catching in this study

[00:26:03] Carolina Reis Oliveira: yeah most of these studies that we do is usually plus forty five years old okay forty five to sixty five some are even older because in that case we wanna address like the skin when it gets like too fragile it's a different study that i can share but for the this like face studies it's usually from forty five to sixty five so it does include like mostly women in men menopause so period and we can see that there is like this really impactful benefit of like helping restore that collagen production and the barrier because obviously skin gonna get also drier because the estrogen you know helps you to keep the moisture and the barrier so most of our studies are in participants that red experience those like significant collagen and decline mh and it's really interesting to see that we can recover some of the and and you know help your skin recover that you know healthy you know glow look

[00:27:13] Dr. Brighten: i know you said a lot of the types we don't know the mechanism by which they work do you know what it is about this peptide that helps that collagen production

[00:27:23] Carolina Reis Oliveira: yeah definitely so what happens is sen cells they are basically not producing collagen they are not functioning well anymore mh and they are gonna start secret securing this inflammation that are gonna induce the cells around the two become zombie as well by reducing sen and cells also some of the inflammation they the signals that they they secret those collagen and degradation so by shutting off these themselves reducing their amount we first are not inducing we're preserving our collagen and second we are maintaining the healthy cells healthy and functional and we even allow them to replicate so they can continue to produce collagen so we're basically eliminating what is like causing aging and the collagen degradation and we allowing your skin to do what it's supposed to do which is like proliferate replicate produce collagen and so we are removing we sometimes we call like the sen essence of the bad the apples you know the ones that are rock so you're like

[00:28:33] Dr. Brighten: when you have a rotten berry in the bunch and you're like i have to get this out before destroys my whole bunch

[00:28:38] Carolina Reis Oliveira: yeah exactly so that's how we you know the peptide is working you know getting that to berry you know rat and berry out and so preserving the healthy so they continue to thrive

[00:28:51] Dr. Brighten: mh so i think you know we've we focused a lot on collagen and fine lines and how your skin will be visibly more youthful and we know that visibly youthful skin there's also a benefit beyond that so i'd love to talk a little bit about why this is important beyond just how we look beyond just know fine and wrinkles that come with the loss of estrogen why should we care about wanting to have these you know sen cells gone and also having the healthiest skin

[00:29:28] Carolina Reis Oliveira: yeah so this is actually one of the main reasons why i got so excited about working in their skin and aging because to me until you know few years ago or maybe until today most people just think of your skin from an aesthetic standpoint and then when i started the studying skin and aging in obviously realizing that your skin is your largest organ as the skin ages and accumulates more of the zombie cells they are secret creating more inflammation not only in your face but throughout your body and since your skin it's basically covering your body that inflammation that is increasing in your skin eventually impacts internally your levels of inflammation and so skin the skin aging process also impacts our internal aging and we actually did a clinical study to validate that and for that study the one that we use like elderly participants when they already have the the skin a little more fragile thing and and so they were over like sixty years old and they used the our face and body lotion for three months we collected their blood you know at baseline and at three months and we saw that just by recovering the strength of your skin the barrier your skin and reducing the inflammation that's coming from your skin we could lower the inflammation in their blood like in some inflammatory cytokines like il eight il six tn alpha interferon so these are all very pro inflammatory cytokines or you know signals that are sales for produced and we saw significant reduction in il eight and we saw a trend in the creating this overall profile of like molecules that are our that they had in their blood so this is studies also published we can link at at the the episode and is again it's the one of the few studies that connecting like the importance of your skin you know impacting your overall health and so i'm fascinated about that and even because obviously the more inflammation that you have in your blood i mean this is associated with chronic disease outside all calls mortality so if you're doing everything that you want you know that you can do to maximize your house i think your skin can be an important step into that you know achieving that the overall you know better health

[00:32:09] Dr. Brighten: in this study the os one peptide that was being applied to their skin and to their body

[00:32:14] Carolina Reis Oliveira: yes okay and they i mean they face in the whole body right

[00:32:19] Dr. Brighten: sorry that's what i meant i was pointing to my face and the realize is like you not everybody's on youtube with us yeah so their face and then their full body and and that's tremendously impactful i actually haven't heard of any research where you apply a skincare product and you see a reduction in in inflammatory cytokines and that also you know as we were talking about hairy menopause menopause before which is when we see such a rapid change in the skin we see the rise in cells we see the inflammation we also see that a large number of women suffer from new onset anxiety depression and even thoughts of self harming and to me i'm now now as a clinician i'm like okay hold up like we're we're looking at gut health we're looking at their diet right we're we're looking at exercise we're looking all these things but it hadn't occurred to me until this moment until hearing about this study that we should also be looking at their skin because right we're always like get outside get your vitamin d like get your son not your shine but also like wear your sunscreen and not really thinking about leveraging a peptide for immune system modulation i'm having like kind of a mind blown moment of like this is really a interesting frontier in terms of having you know we talk a lot about holistic medicine but if we're leaving the skin out of this conversation it's not really that holistic yeah

[00:33:47] Carolina Reis Oliveira: a hundred percent and and it's one of you know our goes at one skin to really include the skin in that conversation because it is one important oregon for overall health and one that we neglect a lot of times and and the skin is a reflection of our you know health but i also send signal to our internal body and so it's like a two way approach that i think we all needed to be aware of and on top of like the implication in our house the other piece that happens as we age and wig our like the our the the ninety seven percent of our skin which is our body is the appearance of like crap and very thin skin right and it's like with minimal menopause you'll see an increase you know a significant increase in crave because of that collagen decline and and that you know body treatment can help with that can help like thick they can the the pi their layer of the skin can help like combating the sen and cells can help your skin to produce more collagen and again so even like the improvement in the in the appearance the texture it's really really impressive like what we have seen from our communities and from our clinical studies in recovery that you know strong resilient aspect of our skin that we have right now but we take granted and then you know later in my life we're were gonna see wow why i didn't you know treat more my arms my my legs and and even like later in life they can start like to bruise easily to you know tear easily so so one area that we also like to bring awareness that we should you know treat and invest early on because eventually that will impact our lives in so many ways

[00:35:41] Dr. Brighten: yeah and i especially think you know as you're talking about this i think about my family members who are in their seventies and there was a situation in our car we have a we've a little chihuahua and our son was like oh let me just like throw the dog on grandma's lap real quick and the dog starts scrambling and i freaked out and had to explain to my son like once somebody's in their seventies they can't have dog nails scratching on their skin like their skin is very fragile and as you're saying all of this i'm like i need to ship them some of these peptide i need to get miss ellis one peptide died for my anxiety sake because i get so worried about that and it's something that that generation has certainly said to me my family member's patience know people have been in contact with have said to me exactly what you just said i didn't worry about my skin until it was too late and i think we have a lot more awareness now we have a lot more technology with protecting our skin but it's good to hear that there's a product that can help because i think sometimes when we talk about aging some things are like well you should have known better in your twenties like how many of us knew better in our twenties right and then it's like there's nothing you can do about it so having something that you can actually come in and intervene with i think it's fantastic you mentioned this concept of basically intrinsic and ex aging so you talked about like you know our our inner body is you reflect of our skin but also our skin is affecting our everybody can you go into a little more detail around that

[00:37:16] Carolina Reis Oliveira: yeah definitely so what do we call intrinsic aging for skin more safe basically the natural aging process your cells are dividing eventually they'll get old and either they will died or they'll become zombie or and that's mainly genetic driven and that accounts for about ten percent of how we age the ten oh about ten percent

[00:37:44] Dr. Brighten: i love this this is amazing

[00:37:46] Carolina Reis Oliveira: okay keep going i yeah the other ninety percent of how your skin ages it's mainly caused by extremely sick factors which are the uv exposure or life you know or habits or if you smoke light pollution your diet if you exercise and so mostly for the skin and i think you know in our inner body this ratio can vary a little bit more but in the skin because obviously your exposure is one of the key drivers of skin aging this extremely stick factor you know it's even more important so we needed to be even more aware of obviously you know sun exposure but also blue light and also pollution and how we're cleansing your skin but obviously you know our diet or exercise or sleep will also affect and and it's good to know that because there's so much that we can do right almost like ninety percent is in our control of how our skin can age and there are so many things that we can do today and obviously you talk a lot about them we can talk more about our skin as well in terms of you know sun protection i'm also fan of you know having the natural light early morning but i also know you know long exposure sun will cause some damage and that's how they become zombie so we know they hire the the exposure of uv damage the more sen the more zombie cells your skin will have and also we know the more zombie cells you have the more you know fine wrinkles loss of you know firm an uneven vuitton dark spots sun spots we will have so i think we have in our hands like the power of like preventing a lot of that

[00:39:43] Dr. Brighten: i wanna go deeper on the sonic exposure but you said blue light and i'm sitting here right now in front of a laptop and so are you how is blue light aging or skin

[00:39:54] Carolina Reis Oliveira: yeah so blue light is basically causing a lot of ox stress producing more free radicals these free radicals are basically molecules that are gonna cause damage in our proteins in our dna and so the bad there are two ways that you can prevent that one is through antioxidants that you will neutralize the free radicals and prevent them from causing damage image and now also sunscreen like in the in our case that we use like zinc oxide the minerals sunscreen they can also protect against blue light so so if you're wearing sunscreen right now it doesn't mean that you are like close to your window necessarily but if you are in front of the screen your sunscreen in our case at the least we we made sure that it's also contains ingredients that will protect against blue light

[00:40:45] Dr. Brighten: i love that that is seriously so good to hear but you said antioxidants what antioxidants should we be looking for to apply to our skin to protect it from ox stress

[00:40:58] Carolina Reis Oliveira: so there are many antioxidants out there i think one important thing to know it's the stability of the entire antioxidants so vitamin mean it's a classic it's a powerful one if it's stable and active it's really easy that you vitamin c will ox so if you are using a product against becoming brown you know that ox that the vitamin c it's probably not active anymore so today there are forms of vitamin c that are more stable we do use a stable form of vitamin c in our sunscreen so other entire antioxidants accents are like green tea sai extract there are lot other plain tech extracts that are you know can be super powerful for an antioxidant on our body lotion we have su far pain and that's another very powerful antioxidant accident

[00:41:55] Dr. Brighten: i'm always using that internally tell people what eat broccoli sprouts but yeah i mean it's so powerful in the research in terms of when we look at cancer formation and you look at so and eating your cr vegetables so i'm actually excited i wanna hear more tell me more about that molecule for your skin

[00:42:16] Carolina Reis Oliveira: yeah basically it's is this really powerful entire accident that it helps again finding this this free radicals and can help your skin to to again be more effective in in fighting that damage and as you point out there studies showing that it can fight like the cancer cells but in the skin will help like your skin repairing damage image more efficiently so if you're if you're able to repair damage your skin will not accumulate those zombie cells that's zombie cells comes from a lot of damage and the the this powerful antioxidants can help with that

[00:42:54] Dr. Brighten: what form of vitamin c should people be looking for

[00:42:59] Carolina Reis Oliveira: i don't have the name right now but i can i can send to you and i will send we can add on the the on the notes of the episode but there is this is stable form of vitamin c that i know that we should look for it to because it's not gonna ox and you know that is gonna be you know active long term

[00:43:22] Dr. Brighten: mh okay so i wanna circle back to the uv conversation because we know right that there's certain times that we want to stay out of the sun but then you said you still want to get your morning sunlight which we know is great for cortisol also what are kind of the general guidelines for maintaining healthy skin when it comes to sun exposure

[00:43:45] Carolina Reis Oliveira: i think the general that i you know take and i recommend that i'm not a dermatologist or a physician i'm a phd but based on my studies and my you know obviously my research in the field is that you wanna avoid first rule obviously is like avoid sunburn right and so sunburn we know that is is definitely correlated to with skin cancer and that we wanna avoid that all costs i think that you know early fifteen minutes like sun exposure in the morning again it depends where you live because even in the morning depending it could be a really really hot so usually the recommendation is uv index under three but it i know that some places you know early morning you can can already be above three but i would say you know i avoid the sunburn fifteen minutes light in the morning and then i apply my sunscreen every day i i usually replace my son's my foundation if the sunscreen because we have distinctive one and to me like if i can have like a a tinted sunscreen that is performing got like my foundation it doesn't give you a lot of coverage but just like you know even your tone a little bit i know that's protecting my skin is like a very nice texture like i don't feel that i have sunscreen screening my face so i do that and so i'm protect i can for blue light for sun you know if we're driving i think that's the other you know parts that sometimes we forget on our hands as well because we're driving but i would say and and i enjoy a lot you know outdoors activity but i'm constantly like reapply sunscreen in a way that i i don't get sunburn but i get a little ten and i think that's fine because your melanin is protecting you against the uv damage as long as you not like getting sunburn so that's my philosophy i know that again people we'll have different opinions but i'm more liking in that tomato ground that i still enjoy life outdoors

[00:46:02] Dr. Brighten: i love that you're saying that though i still enjoy life because sometimes i have friends who are dermatologist and they're like yeah right don't go out in the sun you should never be out there and i appreciate what you're saying about your hands too so eye garden i do love being outside i also love to snorkel and when i go out snorkeling for hours i will wear a shirt that's a uv protection because i'm not going back too if i find you know really cool puffer fish i'm hanging out not going back to replace sunscreen screen but i've have always done like whatever i do to my face my neck my chest do it to the back of your hands as well and because you're gonna go out and you're gonna live life and i really appreciate that message because sometimes you know and let me just say to the dermatologist credit they see a lot of skin cancer so if you're just seeing skin cancer day in and day out you're gonna have a different perspective about things but we can't lose the plot in terms of what are we here for it's to live a full life

[00:47:05] Carolina Reis Oliveira: yeah and i think that's gonna bring you joy that's gonna decrease your cortisol level that's gonna reduce inflammation so i think there is like so much of these other benefits that we're not taking account and it's also helping your internal health in so many ways

[00:47:22] Dr. Brighten: absolutely so we talked about you know the sun exposure what about people listening right now that maybe they were the baby oil era you know those people right i remember my mom putting baby oil on and going out into the sun oh their skin now they've suffered skin damage it are there things that they can be doing now like do some of these antioxidants are they going to offer protection or the ways to reverse that

[00:47:50] Carolina Reis Oliveira: yeah a hundred percent i think the beauty of you know what a science has shown us is that aging is a malleable process it can be reversible and so all of that what we talk today the you know your diet antioxidants the peptide even the red now at you know the right dose and the sunscreen will help like you know reverse part of that process obviously it's gonna be a it's gonna be a gradual process it's gonna take months and years but it is possible with the right to routine and the consistency to really repair that the damage and bring your skin into a healthier younger functional state and so i usually say it's never too late to to start obviously the earlier that you started the better we know that we do start accumulated those zombie cells as early as our in our twenties so oh no yeah for my be in india that like our life is like is the build up of this you know small habits and and so if we are aware if we're lucky to be aware our to and it's bed amazing right like let's use the sunscreen let's use like a good you know moisturizer with a peptide that has you know scientific validation behind and and just maintained that skin like you know younger healthier functional longer it's easier than reverse mh so yeah

[00:49:29] Dr. Brighten: yeah i i shouldn't be a surprise because even osteoporosis right we're always like oh that's the problem when you're in your sixties it's a problem in your twenties and it keeps going and then it manifests in your sixties seventies plus so i am curious though like what what would you say is a good root teen obviously you're not a doctor this is not a prescription but just you have been deep in the research so in terms of someone has had some damage let's say they're fifty plus years old what would be a good daily skincare routine for them

[00:50:03] Carolina Reis Oliveira: yeah i mean i'll i'll share mine with and and probably i can extrapolate for a someone that has more sun damage that i do but i would say start with like you know night cleans your skin with a gentle cleanser there you can double claims or you just like have a gentle cleanser that doesn't disrupt your skin microbiome shouldn't dry out your skin i think at their are fifties primarily we trying to preserve like our skin and in you know the barrier which is really really important for everything else so a gentle cleanser there and something that's not a strip out all of your oils really really important then you are gonna come i would say start to if like a moisturizer that has like you know peptides that has been you know scientifically validated or you know clinically validated and then i would come with the retina now you could add another step of you know antioxidants more specifically that could help with brightening so we know that you know the sea fe lake like it's like one of very powerful blend of antioxidants i'm more fan of antioxidants than the prescriptions once but obviously everyone is in a different phase and it you know you you can go through the prescription route as well one other thing that we have that we recommend it's an ice cream because what do we when we're studying we found that the skin around their eyes is twenty two thirty years older than their skin around you know our face like samples and chicks and and we know that the skin is five times thinner accumulates more of the zombie cells and obviously it's really hard for you to at least for me like i don't put like red now on my eyelids i feel that it's too much already so we formulated an eye cream that has a higher concentration of the peptide and the clinical studies the data is the strongest one in terms of increasing collagen and reducing fine lines and wrinkles even the eyelid that starts to droop a little bit like we could see a bit of a lifting effect and in elasticity so this is the most like powerful product that we have in terms of efficacy and that's primarily it and then you could like apply the rat on top of the moisturizer and as i said and in the morning very simple at least i try to keep a very simple routine i don't clean my skin in the morning again because it's already you know clean from the night before i just rings the water if you have like very oily skin which is usually not the case for fifty old the women just rinse through your your face and then apply your moisturizer in our case our spf already has all the antioxidants so i skipped like i don't need to have another vitamin c and that's it like ready for the day yeah

[00:53:18] Dr. Brighten: well i do have to say that i have used your i cream i've been using that i didn't have any reaction to it he's just by having sensitive skin and it's back to school week and i was joking with my husband that i was like i swear this eye cream is saving me from how tired i really am from actually anyone knowing like nobody knows that i'm actually tired because something i noticed as i enter my forties is that if i don't get great sleep it's like really around my eyes that i will notice it and sleep definitely wasn't great like these last few days is just like you know i don't know if have kids but you get like a thousand emails and there's a thousand things to do before school and i've been so anxious about like don't mess this up for him and so i really appreciate your eye cream it's it is interesting that you said this is the highest efficacy product can you say more about that

[00:54:13] Carolina Reis Oliveira: yeah so for every product that we have we run our internal data and we also run clinical studies that is done by a third party so our internal data when we compare the levels of collagen and that we in do with our eye cream compared to the face it's it's more than double in terms of collagen production and genes associated with aging are also more reduced and for the clinical studies we saw a really strong re improving in hydration so it was like thirty two percent measured by instruments

[00:54:51] Dr. Brighten: there's where why i don't look so tired this leads right there that thirty two percent bump in hydration

[00:54:57] Carolina Reis Oliveira: and they will really help with like smoothing out the the their fine and and we also saw twenty four percent increase in elasticity and i love that all these data it's measured by instruments so it's like you know it's quantified it's not like consumer perception that like i feel you know this way or that way scientist i always look for the hard data and and again with a formula that it's it's validated to be safe for sensitive skin so it's really good for that delicate skin around their eyes mh

[00:55:35] Dr. Brighten: so i wanna shift the conversation because i asked you the care routine of like what if you're in your fifties but i bet there's a twenty something right now being like hold up she said these cells are starting in my twenties and you're just gonna glaze right over this no we're not we're gonna come back to this so don't wanna jump back so let's say someone's in their twenties should they have the same skincare routine as someone in the fifties

[00:55:58] Carolina Reis Oliveira: i think that you can reduce the amount of steps so i think for the plan is like if you don't have like discoloration you i don't think you need the like a vitamin c you can stick to sunscreen a moisturizer like our face moisturizer already has like the peptide that will fight the and cells that will provide some antioxidants accidents and i think that's it i think if you want yeah if you wanna start with have a very light red now but again i would do like few times a week i'll definitely not be aggressive for your skin if it doesn't need to you wanna maintain your skin you wanna make sure that your skin is thriving and you don't want too much on your skin that's like my advice for younger people

[00:56:48] Dr. Brighten: yeah now the other phase of life that women goes through is pregnancy and we we said like you into the pregnancy glow earlier but it's not like that for everyone for some people they get really red and sp melasma is a thing that you know i think a lot of women dread whether they're going to get it or if they have it trying to get rid of it can you talk to us about how pregnancy hormones are impacting the skin

[00:57:13] Carolina Reis Oliveira: yeah and i maybe i was testing that this is not you know one of my main expertise and mainly because it's really hormonal driven so it hormonal implants this is really hard for us to understanding in the lab but there's is something more systemic and so i would probably recommend the you know talking to dermatologist because i know that some of the brightening the the vitamin c could help but i know that some melasma cases you definitely needed to consult to if but with other dermatologist

[00:57:47] Dr. Brighten: mh well i think that's important for women to hear because sometimes we think like we have to diy everything ourselves and sometimes you just need to go to a provider and you know i appreciate that you're like it's really hard in the lab yep that's why we don't have a lot of studies on a lot of these things because hormones are hard just because you know you're pregnant and your neighbors pregnant and your best friends pregnant like doesn't mean you have the exact same hormone profile or that your genetics response to those hormones in the exact same way so it can be really complicated but i do appreciate that at the top of this interview you talk to us about how these peptides can be used in pregnancy because we're seeing more women are having babies in their forties and they're like wait what do i do now because i can't do the re and i can't do the botox and i can't do the lasers and i can't do you know all of the things that people talk about out there which is you know there's a wide variety of things and so knowing that you can still access these peptides and that it's mod inflammation i think is also really interesting as well especially as i consider that as you shift into postpartum we can see a huge inflammatory response just by way of the immune system shifting with the loss of the placenta and the birth of baby

[00:59:13] Carolina Reis Oliveira: yeah no a hundred percent and counteract that inflammation or if like those soothing that's the time that i think you needed to be you know give some extra love to yourself and you know don't don't try too much like you recover and and i haven't had kids yet sorry i'm i'm still to go through that phase hopefully soon but i think we just needed to sometimes be patient as well and and we'll you know with time our body has this beautiful ability to recover and so be gentle to yourself with patient and there are alternatives that are safe that are gentle for your game so you can rely on them as well

[00:59:53] Dr. Brighten: you mentioned earlier there's lifestyle choices that can accelerate skin aging i would love to go through a list of those so people know what are like the things that we should consider avoiding

[01:00:05] Carolina Reis Oliveira: yes definitely so i mean the first one based will start if they again the the sonic exposure that we already talked and i think something that we needed to be mindful that in our daily basis we are being exposed you know you can be by a window you can be commuting and so a lot of people is still like i'm just applying if i'm gonna stay in the sun like for hours i think that should be a daily habit if it's a product that's safe for you i know that there is some concerns around sunscreen out there they can because and they could potentially you know have some implications but there are the safe you know mineral alternatives like the zinc oxide that you shouldn't have any side effects and it can still feel really nice to your skin you need sleep it's another one we know that impacts everything and and and obviously impacts our scheme so much know

[01:01:09] Dr. Brighten: just laughing because i out myself with the sleep

[01:01:14] Carolina Reis Oliveira: no if if you can you know give yourself that yourself like that eight hours like more than eight hours is like how much you're recovering right so how much you're actually resting because that's the time that your body your skin is really repairing all the damage that you were accumulating the whole day so if you don't give your skin the right time like your skin will wake up tired and we you know go through another battle and so i'd say sleep it is it's a really key one a clean you know healthy diet full of antioxidants you wanna avoid sugar that's is gonna increase your inflammation you wanna increase your levels of proteins you can supplement with collagen and that you are gonna give your skin like the building blocks that your skin needs to build your own collagen and doesn't mean that the collagen that your drinking is gonna go straight your skin but you allowing your body to have like the the building blocks that it needs and on top of that the collagen and it can be also antioxidants so it can help in in other ways and it can help with your joints and and other things as well we know that exercise and and all of that also you know the movement impacts your skin and finally you know it's stress i think stress is other one that to me you know running a company it's one that i'm trying to fight and manage the most and and we know that the the increasing cortisol are is gonna you know impact inflammation we also saw you know even like cause things like her thin hair loss that we didn't talk about but again sen cells are also involved the hair and hair loss and stress us is a major driver of her thinking and and so trying to manage that stress medi you know with meditation or whatever you do to kind of a disconnect and and reset i think it's one that most people may ignore based on our busy day lives and and can really impact in your skin so many ways too

[01:03:42] Dr. Brighten: we're gonna come back to the hair loss because there's nobody listening who's gonna let me pass that one up yet you said sugar leading to inflammation as a driver of skin aging can you explain more about that

[01:03:57] Carolina Reis Oliveira: yes so basically what happens when we are eating a diet for of sugar is that sugar gonna bind the two proteins and it's gonna form what do we call a advanced and gl products a e and this is basically making our collagen and more stiff and not like malleable so you're gonna lose like the the firm ness your skin is not gonna be as bouncy sit the more ag that you have in your skin so a a diet pool of sugar will lead it to more ag will lead to inflammation will cause your collagen a be stiff and not like malleable as you wanted we call like cross linking the collagen so it's not like working properly and that's also signaling inflammation to the body so definitely not only that but you know when you eat like either like a piece of meat or bread that's a little burnt it's also full of you know advanced gl location products and you should avoid that the burn piece as well i always like with people around me don't eat at to burn part and some some people love that and like no that funny know

[01:05:14] Dr. Brighten: i have a father love who eat like burnt toast and i'm like no don't but i also have a twelve year old who like is and like a little food patrol at times where he's like is that raw is that overcook cooked like and so he'll get on his grandpa about it like you can't eat that it's not good for you still you know how as you're bringing this up and i'm thinking about like okay so we've got peri menopause menopause we're having lots of collagen we've got these you know gl elements in our skin that are also contributing to the problems that we face in terms of what we're trying to avoid but that the other thing that was coming is like this excess sugar is aging your skin it's inflammatory because of this process but that excess sugar is also what we see connected to the increase in visceral out positive for women which is the fat that packs around their organs which also increases inflammation so just for our listeners to make that connection of like this is you know not just about metabolic health and and we're talking about excess sugar we're not talking about you ate berries we're talking about you know you're eating cake ice cream soda like adding tons of sugar to your coffee you're going past twenty five grams of additional sugar that's coming outside of your natural food sources that can be so problematic for our cardio metabolic health but also our skin health as well and i think that's a really important connection for people to make now we're gonna go into that hair because i know that that peaked listeners attention so you said stress can be a driver of hair loss what else should women be considering if they're experiencing hair loss

[01:06:55] Carolina Reis Oliveira: yeah so one of the things that we realized that we were as we were studying zombies cells in their skin and eventually we all you know i don't know if how many people realize but like your scalp is basically your skin as well i was a continuation of your skin and so our hair follicles are embedded in that scalp that's the skin and that also is aging and it's accumulating those zombie cells and what we found is that their studies is showing that the accumulation of zombie cells in hair follicles because is the major driver of like age related hair thingy which basically comes around our fifties is different from the mayo or female pattern hair loss that's more like hormonal mono driven like related but also stress can cause more accumulation of sen cells in the hair molecules and that can lead to hair and hair loss we even validated this in the lab that windows we supposed the hair fo cells with a hormonal stress and and then it caused sen cells and then we treated the peptide and we could reverse that like sun cells again we were looking for a solution that all the prevent or reverse her and hair loss without including like drugs that can you know have some side effects you know they're like many drugs out there that can block you know the conversion of testosterone to d which we know d is basically this form of testosterone that bind in the hair follicles and in those hair shrinking but all of these drugs can have so many side effects you don't wanna take if you're pregnant you definitely don't wanna take you know postpartum so and postpartum is one you know pure of your life that you're likely gonna experience hair loss because you have like a peak in estrogen and then there is a a decline and then you're gonna experience some shedding and so we we basically develop a hair serum that contains the same peptide that fights this zombie cells in the skin but now fighting the zombie cells in our hair follicles just so it's pretty safe it has a beautiful results in terms of increasing hair density and hair thickness it also improves your skin microbiome because our microbiome also changed with aging and improves your scalp health and i think it's another area that we we usually treat our schemes to prevent fine and wrinkles but we don't treat our sk to prevent cleaning and hair loss that's it's likely gonna happen at some point of your life you know at at least like seventy eighty percent of you know people men and women experience some hair and hair loss throughout their lives and i think having this proactive more like preventative approach is one that we should start incorporating but i also can be used if you're already experiencing you know some time of shedding or hair cleaning we have seen you know great re grow reg growth in terms of recovering that healthy you know hair and growth cycle

[01:10:35] Dr. Brighten: mh and this is the same os one peptide that you were talking about earlier i'm curious so you've seen reg growth has it been quantified like how much hair is able to come back and and how quickly does it come back

[01:10:50] Carolina Reis Oliveira: so this usually takes longer hair

[01:10:53] Dr. Brighten: hair this is so lame like that takes so long to bring it back

[01:10:57] Carolina Reis Oliveira: they takes usually from three to six months after six months from our clinical study we saw forty percent increase in hair density and forty percent increase in hair thickness so that's really significantly and impressive because yeah the the the hair volume that was becoming thinner it's now like forty percent thicker so it is stronger is gonna stay in that hair growth cycle for longer and and so we have from our studies is like really i mean strong quantitative results we have really strong you know before and after that obviously everyone wants to say but i think really interesting to see that combating these zombie cells in our hair follicles because there's also way to combat combat like hair loss and hair thinking

[01:11:51] Dr. Brighten: mh we typically so in medicine what what the belief is currently is that once mini maturation occurs at the hair fo so the shaft is becoming thinner and thinner that that's irreversible yeah are you saying that you've you guys actually have seen the hair become thicker again

[01:12:13] Carolina Reis Oliveira: yes it's harder to quantify exactly the same hair for yeah totally yeah but i say that if it if if you're starting the mini maturation phase it's not completely like you know to the end yet you can reverse that so it always depend the phase that you are but at what you don't want is that hair fo could to completely to die and so that you cannot recover but if it's in the beginning of the mini mini immunization phase you can still recover that hair falling

[01:12:48] Dr. Brighten: mh that's so interesting and is this this is a serum do you have to apply it a couple times a day is it once a day

[01:12:56] Carolina Reis Oliveira: yeah usually we recommend it twice a day or at the least once a day it's a it's a water based serum so it shouldn't you know make your scalp your your hair greasy you can still style you know blow dry whatever you you like to do but ideally by a day morning and night thought you can apply on a wet hair or dry hair but yeah the consistency here is the most important thing

[01:13:27] Dr. Brighten: and consistency day and night if possible it's it makes it easy if you're like wet hair dry hair because that i could just see that it being an easy part of the routine and then give it at least six months to be able to really see the outcomes there yeah which is pretty typical i mean anyone who has has has had a baby as you were saying in postpartum nose that at four to six months postpartum your hair gonna fall out and then it's gonna be by the time hopefully your baby starts sleeping around twelve months that you start seeing your hair comb back and still they don't they don't always sleep but i would imagine you know using this serum it's helpful but if you're still doing things like skipping sleep smoking not practicing stress reduction that might be able to negate some of the effects

[01:14:17] Carolina Reis Oliveira: yeah a hundred percent yeah that little definitely impacted the so in the end we are always talking talking about like a holistic approach right and so we know that they stress the lack of sleep will will impact but you can minimize so you know there is obviously sometimes you can't tackle everything at the same time but it you know if you can add that layer of support your scalp will help you know it could be better yes if your internal bodies healthy yes but i think i wouldn't not do it because you can't do everything at this thing

[01:14:56] Dr. Brighten: mh and i know that for certain hairstyles like people don't wash their hair every day does it does that have an impact like do need to be washing your hair day and applying the serum or is it something that you know if you have a particular hair type that you're like i need to it every other day or i get it styled a certain way i can't wash it for several days with that you know negate the effects or does

[01:15:18] Carolina Reis Oliveira: the product build up the product itself shouldn't build that but it's very light they should have absorb release i think if there is a build up of you know oils and other you know dirt may of like the day today that can impact the absorption of the product so obviously a clean scalp will absorb better but i yeah i think you know i i wash my hair throughout their day and i still wear every day and and i think that's totally fine

[01:15:48] Dr. Brighten: and are you using it preventive i used this very personal question i always that's too

[01:15:54] Carolina Reis Oliveira: personal like the you know male female pattern hair loss in running my family so i know you know how impactful you know in our mental health and you know emmanuel anyways hair can be to usually because yeah when you start like seeing your parts like showing it definitely has an impact so i use both you know i i actually wanna reverse and so i do other things i do the the hair like therapy sometimes i do the p and so i'm trying everything because i'm on that phase of you know trying to preserve and you know reg grow as much as possible because i already feel like the cleaning and that's that's not fun no no for sure

[01:16:49] Dr. Brighten: i have hypo i remember when before i was diagnosed losing my hair and just like clumps of it coming out and it is until you've gone through it you don't understand how distressing it is on a a mental health level for people who know they have you know family fam hair loss or you know they're there's just like i wanna keep my hair for as long as possible as lush as as possible like when should they you know consider using this as a preventative measure this peptide

[01:17:24] Carolina Reis Oliveira: yeah i think if they have this you know related bald in their family i would start as early as their twenties if they don't have and they would just wanna prevent i probably starting my thirties i wish i had this product when i was in my thirties because i think it's easier to maintain my hair but if you have in your genetics i'll would start probably in your twenties end and i know that some people can start even you know getting involved around your toy is so that's one thing that they're earlier the better if you have in your family

[01:18:03] Dr. Brighten: yeah i i think that's a good thing for listeners to consider i'm also curious are there are things that people are doing unknowingly that's maybe damaging their hair or you know they can be having a negative impact i mean other than like the stress to sleep some of the things that we've talked about

[01:18:25] Carolina Reis Oliveira: yeah definitely you needed to be careful with like the chemicals the bleaching of your hair how you know how are you dying your hair those came because that golden your scalp they can definitely impact your scalp microbiome your hair follicles because so i would be aware of that i would be aware of sun exposure on your scalp because obviously your if your scalp is getting damaged and some that's also gonna impact your you know the aging of your scalp and consequently your hair follicles because and as always like the products that you wash your hair your clean your hair you need to ideally they would be you know they would contain like safe ingredients because otherwise

[01:19:17] Dr. Brighten: you're

[01:19:17] Carolina Reis Oliveira: are causing more irritation your scalp more redness and that's all contributing to that you know aging process as we know

[01:19:25] Dr. Brighten: mh you've brought up the skin microbiome on the scalp microbiome what do you think people should know about that

[01:19:31] Carolina Reis Oliveira: i think people should know that our skin or scalp are good we have this microbes and you know bacteria fungi that are important to maintain the health of our bodies and you know they produce certain meta they protect you know our our skin they they help even like met obviously in our gut like meta you know our food and and absorbing the nutrients so maintaining that microbiome like healthy in a homeostasis it states really really important and when that microbiome is disrupted they're good like we have leaky good we you know in our skin you can have a lot of things related to you know either eczema or psoriasis or you can have acne that's also this regulation it could be hormonal as well but it like it it could manifest if your micro microbiome is regulated and your scalp you're gonna you can have like a scalp a flake scalp and and then and all of those things can be associated with for like an non healthy and unbalanced microbiome so protecting that microbiome basically means like not using things that are stripping away all of your good you know bacteria so it can be it you can have like you can use like soaps of detergent that are really stripping that good bacteria and and and use products there are products obviously you know probiotics for the get but they are like a in our scope here and we have like a a pre for this scalp as well that helps like nurture that the microbiome so it will continue to you know perform at it's best

[01:21:22] Dr. Brighten: that's so interesting of course i'm familiar with pre and for my audience i will link to the gut health episode where i talked all about pre probiotics internally how they feed those critters that grow in your gut and it's one of the best things that you can do for microbial diversity i mean everybody's always looking at like how do we eradicate things and and why do i have this d and we need to be consuming pre probiotics but the concept of actually putting pre probiotics on your scalp is totally new to me can you say more about that

[01:21:52] Carolina Reis Oliveira: yes so basically our you know scalp microbiome can change with aging and they're ways that you can help like shift that microbiome to a healthier one so you can support the growth of the good bacteria that will support the growth of your hair follicles because and you can decrease the growth of the bed bacteria that is associated with hair loss so there are ways that you can do this with pre probiotics so nurturing the right bacteria and when you have the right bacteria usually they prevented the growth of the bad bacteria and the same with fungi a lot of ingredients can help like mod that microbiome in a way that it you have the right ones there that are supportive to your scalp health and and that's one thing that impacts not only again your scalp but obviously your hair growth

[01:22:55] Dr. Brighten: yeah then i think probably is a big light bulb moment for a lot of people who struggle with you know fungus on their scalp it's something that's really common nobody wants to talk about it because it's really shameful and i think this is gonna be one of those big breakthrough moments for people as well hearing that like there are actual ways to cultivate the microbiome of your scalp because we also know in the gut when we have fungal over growth in the vagina when we have fungal over growth we have to cultivate the good bacteria if we want to prevent that from reoccurring so that is absolutely fascinating will link to all of the products that we've discussed today including that scalp serum because i know people are definitely going to be i can already see them in the comments like give me the link to that but i wanted to finish up by asking you if you could correct one major misconception women have about skin aging what would that be

[01:23:51] Carolina Reis Oliveira: first of all skin aging and like having your best skin will mean different things for you know every person i think we all should look for that skin that make us feel confident that make us feel good and and a healthy skin usually is halfway there like a healthy skin is a good looking skin is a skin that it's telling you that you you know your body is healthy and obviously you can go further if you wanna do the the injectable and the botox but i think to me as i age i i try to optimize my skin in a way that i'll feel and look my best but i'm not after you know that the flawless and some people are after that the glass skin that's like a completely perfect skin i'm looking for my best skin that i still feel you know myself but not in a way that i could you know be doing too much to my skin in in a way that i'm you know kind of disrupting you know what my skin is supposed to be and to for my body so in the end i think about aging skin is something that you are optimizing and we shouldn't necessarily fight for like that twenty year old the skin again but like embrace that you know even some lines you know if they're an expression of the memories and the left that you had throughout their life that's that's my philosophy i still would do you know a lot of things to look you know at my best but i think i tried to respect that balance so that's that's my philosophy i think in the end like less is more and there is this still ways that you can achieve that great look and you know prioritizing health i think health you know should always come first

[01:26:00] Dr. Brighten: that's such a refreshing message i think for women to hear especially in the age of the kardashians no shade to them i am all about whatever makes you happy and how you wanna live your life i support you in making your decisions and yet i think sometimes when we see radical face lift send all of these procedures women feel like there's a new bar a new hurdle that they have to be leap over and so to hear a message from a scientist who has a skincare line saying that you know embracing the natural process but nourishing your skin that it can have the best integrity the best of health is just a beautiful beautiful way to end this conversation so i appreciate you sharing your expertise for all of these aha moments that i think our listeners are gonna really appreciate and for the work that you're doing to transform skincare for women for the better

[01:26:58] Carolina Reis Oliveira: oh thank you ja yeah this was a wonderful conversation thanks for allowing me to share a little bit with your community and thanks for all that you do i think you're you know obviously a beacon of like so much great information and inspiration for a lot out there

[01:27:16] Dr. Brighten: oh well thank you thank you so much for joining the conversation if you could like subscribe or leave a review it helps me so much in getting this information out to everyone who needs it if you enjoyed this conversation then i definitely want you to check out this